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Figure 2 | In Silico Cell and Tissue Science

Figure 2

From: Probabilistic Voxel-Fe model for single cell motility in 3D

Figure 2

Geometry of the microfluidic device and details of domain and cell mesh. Left: two channels (gray) are separated by collagen I gel (cyan). Pressure and chemical gradients are established between inlet (purple) and outlet (orange) boundaries. A box-like domain (right) is taken from the central part of the gel to simulate the mechanical analysis and the cell migration. This domain is discretized with voxels of 3 μm, some of them considered cell-voxels and forming an initially spherical shape of about 30 μm of diameter embedded in the ECM to perform the mechanical and migration simulation.

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