Figure 5

Fluid chemical analysis in a 3D microdevice. A) The velocity field present higher values in the gel zone between micropilars, reaching a maximum of 2.96 μm/s. The streamlines in the central part are mostly parallel to the horizontal direction. B) The pressure drop across the microdevice shows a linear decrease through the gel and constant values at the inlet and outlet (40 and 0 Pa respectively). This analysis is computed (using COMSOL) once at the beginning of the simulation and its results are interpolated to a box-like voxelized mesh, where the mechanical analysis is performed and the cell migration is studied.