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Table 1 Parameters for the fluid-chemical and mechanical analysis

From: Probabilistic Voxel-Fe model for single cell motility in 3D

Symbol

Variable

Value

ΔP

Pressure gradient at the microdevice

40 [Pa]

D

Diffusivity constant

10-9 [m2/s]a

κ

Gel permeability

10-13 [m2]a

μ

Fluid viscosity

103 [Pa.s]a

ρ

Fluid density

103 [kg/m3]a

ΔC

Chemical gradient

1 [mol/m3]

K pas

Passive resistance of cell cytoskeleton

1 [kPa]b

K act

Actin stiffness

10 [kPa]b

ϵmax, ϵmin

Maximum/minimum cell strain

-0.4,0.4b

σ max cort

Maximum stress of the acto-myosin (AM) system at the cortex zone

2.5 [kPa]b

σ max cyto

Maximum stress of the acto-myosin (AM) system at the cytoplasm

1.5 [kPa]

  1. a[13], b[22].