Table 2 Constant parameters of the probability functions

$p_{+}^0,p_{-}^0$

Minimum probabilities of voxel addition/removal

0.1, 0.1

$p_{+}^{\text{max}},p_{-}^{\text{max}}$

Maximum probabilities of voxel addition/removal

0.8, 0.4

$k_{+}^0,k_{-}^0$

Addition/removal rate

0.4, 0.4 [min^-1]

λ₊^σ, λ_-^σ

Sensitivity constants of addition/removal regarding cell stress magnitude

0.0035, 0.0035

${\lambda }_{+}^{\mathit{\Delta }\mathit{\sigma }},{\lambda }_{-}^{\mathit{\Delta }\mathit{\sigma }}$

Sensitivity constants of addition/removal regarding cell stress gradient

0.004, 0.004

λ₊^C, λ_-^C

Sensitivity constants of addition/removal regarding chemical concentration

0.3, 0.3

λ₊^F, λ_-^F

Sensitivity constants of addition/removal regarding flow direction

0.004, 0.004

_dt

Time step

5 [min]