From: Etiology of Keratoconus: proposed biomechanical pathogenesis
 | Description | Geometry | Mechanical properties | ||
---|---|---|---|---|---|
 |  | Minimal thickness [μm] | Region diameter [mm] | Elastic modulus [MPa] | Region diameter [mm] |
Case 1 | Nominal | 500 | - | 0.4 | - |
Case 2 | Mildly thin | 350 | 2 | 0.4 | - |
Case 3 | Severely thin | 140 | 2 | 0.4 | - |
Case 4 | Small defect | 350 | 0.35 | 0.4 | - |
Case 5 | 50% more compliant | 500 | - | 0.2 | 4 |
Case 6 | 70% more compliant | 500 | - | 0.12 | 4 |
Case 7 | 90% more compliant | 500 | - | 0.04 | 4 |
Case 8 | Off-center thin | 250 | 2 | 0.4 | - |
Case 9 | Off-center more compliant | 500 | - | 0.04 | 2 |
Case 10 | Concentric stiffening | 500 | - | 0.35 | 5 |
0.6125 | 5-6 | ||||
0.875 | 6-7.5 | ||||
1.225 | 7.5-11 |